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Wilbur B. Bowne,

MD, FACS

Title: Professor

Practices: Drexel Surgery, Drexel Radiation Oncology

Specialty: General Surgery, Surgical Oncology, Minimally Invasive Surgery

Locations:

Drexel Surgery
219 N. Broad Street
The Arnold T. Berman, MD Building, 8th Floor
Philadelphia, PA 19107
Maps & Directions

Phone: 215.762.1647
Fax: 215.762.8389

Education

  • MD - State University of New York Health Science Center of Brooklyn

Awards & Honors

  • Honorary co-chair, Pancreatic Cancer PurpleStride Philadelphia Walk [PDF] (2015)
  • The Lutheran Medical Center, Department of Surgery, Excellence in Teaching Award (2005)
  • The Mount Sinai School of Medicine, Student Council House Staff Excellence in Teaching Award (2002)
  • The Mount Sinai School of Medicine, Department of Surgery, Medical Student Teaching Award in Surgery (2002)
  • The David A. Dreiling Award for Academic Achievement, The Mount Sinai School of Medicine, Department of Surgery (2002)

Clinical Services

Minimally invasive surgery, Pancreatic disease, Hepatobiliary surgery, Surgical oncology, Gastrointestinal cancers, Pancreatic cancer and related diseases, Pseudomyxoma peritonei

Biography

Wilbur B. Bowne, MD, FACS, is a graduate of SUNY Downstate Medical School. He completed surgical training at Mount Sinai School of Medicine and surgical oncology laboratory and clinical fellowships at Memorial Sloan Kettering Cancer Center in New York. Thereafter, he obtained additional training in minimally invasive/laparoscopic surgery.

Prior to being recruited to Drexel University College of Medicine, Dr. Bowne served as chief of the Section of Surgical Oncology at Downstate Medical Center where he was the American College of Surgeons cancer liaison physician. Dr. Bowne's expertise includes surgery for the pancreas, liver, bile duct, and gastrointestinal tract.  He leads a multidisciplinary cancer team which offers a new state-of-the-art procedure, called hyperthermic intraperitoneal chemotherapy (HIPEC), to patients with advanced abdominal cancers, including colon, ovarian, appendiceal and gastric cancers, peritoneal mesothelioma, low-grade sarcomas, and pseudomyxoma peritonei. Dr. Bowne and this new breakthrough treatment option were featured in the April 2013 edition of Pulse [PDF].

He is extensively published with over 100 peer-reviewed articles, abstracts, and book chapters. He is a sought after speaker on the topic of gastrointestinal oncology. Dr. Bowne is also the recipient of numerous awards for teaching and extramural funding for his research in pancreatic cancer.

Dr. Bowne takes great pride in being a member of Drexel's multidisciplinary cancer team, which treats the most complex patient situations no matter the circumstances or nature of the condition.

Videos

Fellowships

  • Research - Memorial Sloan-Kettering Cancer Center (1996-1999)
  • Surgical Oncology - Memorial Sloan-Kettering Cancer Center (2002-2004)
  • Laparoscopic/Minimally Invasive Surgery - State University of New York Health Science Center of Brooklyn (2004-2005)

Residencies

  • Surgery - Mount Sinai School of Medicine, Mount Sinai Hospital (1999-2002)

Internships

  • Surgery - Boston University School of Medicine (1994-1996)

In the Media

Publications

Selected Publications

"Anti-Cancer Peptides from the Ras-P21 Proteins"
M.R. Pincus, M. Fenelus, E.S. Yahzdi, V.Adler, W.B. Bowne and J. Michl
Current Pharmaceutical Design, In press, (2011)

"The Anti-cancer peptide, PNC-27, adopts an hdm-2 binding conformation in solution and binds to hdm-2, uniquely expressed in the membranes of cancer cells, resulting in transmembrane pore formation and cancer cell death"
E.S. Yahzdi, W.B. Bowne, V. Adler, K.A. Sookraj, V. Wu, V. Shteyler, H. Patel, W. Oxbury, P. Brandt-Rauf, M.E. Zenilman, J. Michl and M.R. Pincus
Proceedings of the National Academy of Science USA, 107 (5): 1918-23 (February 2010)

"PNC-27 acts as the intact peptide in inducing pore formation to occur in the membranes of cancer cells"
K.A. Sookraj, W.B. Bowne, V. Adler, E.S. Yhazdi, V. Wu, H. Patel, W. Oxbury, J. Michl and M.R. Pincus
Cancer, Chemotherapy, and Pharmacology, 66(2):325-31 (July 2010)

"Perforated Appendicitis Presenting as a Thigh Mass"
K.A. Sookraj, W.B. Bowne and B.C. Ghosh
The Journal of the American College of Surgeons, 208, (6): 1142 (2009)

"IgE Antibodies from Pancreatic Cancer Patients Mediate Antibody-Dependent Cell Mediated Cytotoxicity (ADCC) Against Pancreatic Cancer Cells"
S.L. Fu, S.L. Pierre, T. Smith-Norowitz, M. Hagler, W.B. Bowne, M.R. Pincus, C.M. Mueller, M.E. Zenilman and M.H. Bluth
Clinical and Experimental Immunology, 153(3):401-9 (September 2008)

"Sophorolipids and their Derivatives are Lethal Against Human Pancreatic Cancer Cells"
S. Fu, S. Wallner, W.B. Bowne, M.E. Zenilman, R. Gross and M.H. Bluth
Journal of Surgical Research, 148 (1): 77-82 (2008)

"Two Peptides Derived from ras-p21 Induces Either Phenotypic Reversion or Tumor Cell Necrosis of ras-Transformed Human Cancer Cells"
V. Adler, W.B. Bowne, K. Ikram, J. Michl, F.K. Friedman, E. Chin, M.E. Zenilman and M.R. Pincus
Cancer, Chemotherapy and Pharmacology, 62(3):491-8 (August 2008)

"The Role of the Assistant in Laparoscopic Surgery: Important Considerations for the Apprentice in Training"
A. Chui, W.B. Bowne, K.A. Sookraj, A. Fingerhut, M.E. Zenilman and G.S. Ferzli
Surgical Innovation, 15(3):229-36 (September 2008)